If TAVR Cannot Be Transfemoral, Then What?

If Not Turing's Test, Then What?

ence, then it will be worthwhile to identify good problems, and even more worthwhile to discover the attributes that make them good problems. This discovery process is necessarily empirical, so we examine several challenge problems, beginning with Turing’s famous test, and more than a dozen attributes that challenge problems might have. We are led to a contrast between research strategies—the s...

Too many pedodontists? If so, what then?

Late False Aneurysm Formation After Transfemoral TAVR.

A n 82-year old women presented with a non– ST-segment elevation myocardial infarction. She had undergone coronary bypass surgery 25 years earlier, and a transcatheter aortic valve replacement (TAVR) 28 months previously. The TAVR procedure was reported to be complicated only by vascular access problems. Urgent coronary angiography at time of the current presentation showed stenosis in a saphen...

Simulating what cannot be simulated

The background to these notes is the expectation that mathematical modelling and simulation is going to play increasingly important role in the understanding of the organization and control of genetic-, metabolic-, and signalling pathways. I am going to argue that for modelling and simulation to help our understanding of cellular dynamics, the current practice of experimental design has to chan...

If not appendicitis, then what else can it be? A retrospective review of 1492 appendectomies.

OBJECTIVE To audit the appendectomies at our institute, and summarise atypical pathological results with a discussion of appropriate management. DESIGN. Retrospective study. SETTING Regional hospital, Hong Kong. PATIENTS All patients who underwent appendectomy for presumed acute appendicitis from June 2003 to June 2008 were recruited. Incidental appendectomy was excluded. Patient demographi...